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CHIRAL-CBH 高效液相色譜柱
CHIRALPAK® CBH HPLC Column
| 產(chǎn)品編號： | 3453339 |
| 產(chǎn)品類別： | 色譜柱 |
| 純度規(guī)格： | 5 μm particle size, L × I.D. 5 cm × 3 mm |
| 包裝規(guī)格： | 1 EA |
| 市場價： | 23750元 |
| 優(yōu)惠價： | 立即咨詢 |
CHIRAL-CBH 高效液相色譜柱
CHIRALPAK® CBH HPLC Column
基本信息
| eCl@ss | 32110501 |
| NACRES | SB.52 |
| General description【一般描述】 | Hermansson described the use of natural proteins immobilized onto a silica support for chiral separations in 1983 (1). Proteins contain a large number of chiral centers of one configuration, and many other sites that contribute to the general retention process. Used primarily for the separation enantiomers of basic compounds, CHIRALPAK CBH phase has cellobiohydrolase as the chiral selector immobilized on spherical 5 μm silica particles. Used in reversed-phase mode, retention and enantioselectivity is regulated by changes of pH, buffer concentration and organic modifier. The mobile phases are mixtures of phosphate or acetate buffers and organic solvents such as 2-propanol or acetonitrile. The column is preferably used for the separation of enantiomers of basic drugs, particularly compounds containing one or more nitrogen atoms along with one or more hydrogen-bonding groups (alcohol, phenol, carbonyl, amide, ether, ester, etc.). Features:
(1) Hermansson, J. Direct liquid chromatographic resolution of racemic drugs using a1-acid glycoprotein as the chiral stationary phase. J. Chromatogr. A, 1983, 269, 71-80. |
| Recommended products【推薦產(chǎn)品】 | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Legal Information【法律信息】 | CHIRALPAK is a registered trademark of Daicel Corp. |
產(chǎn)品性質(zhì)
| material【物料】 | stainless steel column |
| Quality Level【質(zhì)量水平】 | 100 |
| product line【產(chǎn)品線】 | CHIRALPAK® |
| packaging【包裝】 | pkg of 1 ea |
| manufacturer/tradename | CHIRALPAK® |
| parameter【參數(shù)】 | 137 bar pressure (2000 psi) 20-30 ℃ temperature 40 ℃ max. temp. |
| technique(s) | HPLC: suitable |
| L × I.D.【長度 × 內(nèi)徑】 | 5 cm × 3 mm |
| matrix【基質(zhì)】 | fully porous particle |
| matrix active group【基質(zhì)活性基團】 | cellobiohydrolase phase |
| Particle size【粒徑】 | 5 μm |
| operating pH | 2-8 |
| separation technique【分離技術(shù)】 | chiral |
